Heart Scan Can Fine-Tune Risk Estimate for Patients Considering Statins
By GINA KOLATA
OCTOBER 5, 2015
Treatment guidelines suggest that nearly half of those over age 40 — nearly 50 million people in the United States — at least consider a cholesterol-lowering statin to reduce heart attack risk.
But a new large study of people who had an inexpensive heart scan found that half of those who were statin candidates had no signs of plaque in their heart and very little chance of having a heart attack in the next decade.
Some cardiologists say the results could go a long way toward helping patients make a more informed choice about whether to begin taking the drugs.
The test is a CT scan that looks for calcium in coronary arteries, a signal that plaque is present. It used to be expensive — about $500 — but now typically costs between $75 and $100. Still, it is generally not covered by insurance and so is not often used to assess risk. The X-ray dose is about that of a mammogram.
Advocates for the scan say it should be used to “de-risk” people. It can let those who do not want to take statins know whether their chance of a heart attack is actually extremely low.
“Maybe this is a tool to actually do less,” said Dr. Harlan M. Krumholz, a Yale cardiologist and senior author of the paper, published on Monday in the Journal of the American College of Cardiology.
For those who have no objections to taking statins, there is no need for a heart scan, Dr. Krumholz said. But for those who are reluctant to take them, he said, “I am willing to use this to refine their risk estimate.”
Others say the test can lead to an array of other medical problems, some of which are gravely serious.
“The only reason to do things is to feel better or to live longer,” said Dr. Peter Libby, a cardiovascular disease specialist at Harvard’s Brigham and Women’s Hospital. With the scans, he said, that has yet to be established.
Heart researchers have long known that plaques in coronary arteries start out as pimplelike bumps but get waxy and hard and filled with calcium as time passes. Calcium shows up as white flecks in CT scans. The hard plaques are not the dangerous ones — it is the softer ones that rupture and cause a heart attack. But the amount of calcium in arteries can give a good idea of the presence or extent of coronary artery disease.
Dr. Krumholz and Dr. Khurram Nasir, a preventive cardiologist at Baptist Health South Florida, who conceived the new study, reasoned that research on heart scans had not been designed to help doctors make treatment decisions they face today.
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